Golgicide A-2

Name: Golgicide A-2
Brand: TargetMol
SKU: T38818
Rating: 4.5 (1 reviews)

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Catalog No. T38818Cas No. 1394285-50-7

Alias Golgicide A-2, GCA-2

Golgicide A-2 (GCA-2), a derivative of Golgicide A (GCA), is the highly active enantiomer of GCA. It exhibits exceptional selectivity and efficiency in eradicating An. stephensi larvae, making it valuable for dengue virus-related research.

Golgicide A-2

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Catalog No. T38818Alias Golgicide A-2, GCA-2Cas No. 1394285-50-7

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
1 mL x 10 mM (in DMSO)	$416	7-10 days	7-10 days

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Golgicide A-2 (GCA-2), a derivative of Golgicide A (GCA), is the highly active enantiomer of GCA. It exhibits exceptional selectivity and efficiency in eradicating An. stephensi larvae, making it valuable for dengue virus-related research.
In vitro	GCA-2 demonstrates potent biocidal activity against both Ae. Aegypti and An. Stephensi larvae. Moreover, it exhibits pronounced selective cytotoxicity towards An. Stephensi larvae, achieving a mortality rate of 83.4%[1].
Synonyms	Golgicide A-2, GCA-2

Chemical Properties

Molecular Weight	284.31
Formula	C₁₇H₁₄F₂N₂
Cas No.	1394285-50-7
Smiles	[H][C@]12CC=C[C@@]1([H])c1cc(F)cc(F)c1N[C@H]2c1cccnc1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

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You can also refer to dose conversion for different animals. More Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc