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Anti-SMAD6 Antibody (4J476)
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Catalog No. TMAC-03800
Alias Smad6, SMAD6, SMAD family member 6 (SMAD 6, Mothers against DPP homolog 6, Mothers against decapentaplegic homolog 6, MADH6, MAD homolog 6, hSMAD6)
Anti-SMAD6 Antibody (4J476) is a Mouse antibody targeting SMAD6. Anti-SMAD6 Antibody (4J476) can be used in WB.
Anti-SMAD6 Antibody (4J476)
Anti-SMAD6 Antibody (4J476)
😃Good
Catalog No. TMAC-03800Alias Smad6, SMAD6, SMAD family member 6 (SMAD 6, Mothers against DPP homolog 6, Mothers against decapentaplegic homolog 6, MADH6, MAD homolog 6, hSMAD6)
Anti-SMAD6 Antibody (4J476) is a Mouse antibody targeting SMAD6. Anti-SMAD6 Antibody (4J476) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $428 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-SMAD6 Antibody (4J476) is a Mouse antibody targeting SMAD6. Anti-SMAD6 Antibody (4J476) can be used in WB. |
| Synonyms | Smad6, SMAD6, SMAD family member 6 (SMAD 6, Mothers against DPP homolog 6, Mothers against decapentaplegic homolog 6, MADH6, MAD homolog 6, hSMAD6) |
| Clone | 4J476 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of SMAD6 on different cell lysates using anti-SMAD6 antibody at 1/1,000 dilution. Positive control: Lane1: A431, Lane2: A431, Lane3: Hela, Lane4: Jurkat. |
| Application | |
| Recommended Dose | WB: 1:500-1000; |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
| Research Background | Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation (2-5,8). Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 53 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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