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Trichloroacetic acid

Catalog No. T40875 Copy Product Info
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Trichloroacetic acid, commonly used for facial chemical resurfacing, is a metabolite of trichloroethylene, believed to contribute to its hepatocarcinogenic effects in mice.

Trichloroacetic acid

Copy Product Info
🥰Excellent
Catalog No. T40875

Trichloroacetic acid, commonly used for facial chemical resurfacing, is a metabolite of trichloroethylene, believed to contribute to its hepatocarcinogenic effects in mice.

Trichloroacetic acid
Cas No. 76-03-9
Pack SizePriceUSA StockGlobal StockQuantity
1 mL x 10 mM (in DMSO)$50InquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding.
For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Trichloroacetic acid, commonly used for facial chemical resurfacing, is a metabolite of trichloroethylene, believed to contribute to its hepatocarcinogenic effects in mice.
In vitro
Trichloroacetic acid (TCA), a prevalent byproduct of drinking water disinfection, induces a range of liver effects in mice, such as hepatomegaly and liver tumors. Additionally, it serves as an oxidative metabolite of trichloroethylene (TCE), a commonly used degreasing solvent subject to extensive environmental exposure, similarly resulting in hepatomegaly and liver tumors in mice[3].
Chemical Properties
Molecular Weight163.39
FormulaC2HCl3O2
Cas No.76-03-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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