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Rosmantuzumab (Synonyms: OMP-131R10)

Catalog No. T77750 Copy Product Info
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Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3). Rosmantuzumab has potential antitumor activity and can be used to study advanced relapsed refractory solid tumors.

Rosmantuzumab

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Catalog No. T77750
Synonyms OMP-131R10

Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3). Rosmantuzumab has potential antitumor activity and can be used to study advanced relapsed refractory solid tumors.

Rosmantuzumab
Cas No. 1684393-04-1
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$228-In Stock
5 mg$589-In Stock
10 mg$959-In Stock
25 mg$1,420-In Stock
50 mg$1,920InquiryInquiry
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3). Rosmantuzumab has potential antitumor activity and can be used to study advanced relapsed refractory solid tumors.
In vivo
Rosmantuzumab (25 mg/kg; intraperitoneal injection; once a week; for 4 weeks) significantly protects animals from developing liver fibrosis[1].
Rosmantuzumab (25 mg/kg; intraperitoneal injection; once every two weeks; for 6 weeks) in a bleomycin-induced pulmonary fibrosis mouse model significantly inhibits skin thickness, collagen deposition, and the number of α-SMA-positive cells[1].
SynonymsOMP-131R10
Reactivity
Human
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetRSPO3
Chemical Properties
Molecular Weight150 kDa
Cas No.1684393-04-1
Relative Density.no data available
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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