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2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE

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Catalog No. T8602Cas No. 13947-21-2

2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).

2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE

2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE

😃Good
Catalog No. T8602Cas No. 13947-21-2
2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).
Pack SizePriceAvailabilityQuantity
2 mg$30Backorder
5 mg$43Backorder
10 mg$61Backorder
25 mg$110Backorder
50 mg$165Backorder
100 mg$248Backorder
200 mg$368Backorder
1 mL x 10 mM (in DMSO)$46Backorder
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Product Introduction

Bioactivity
Description
2-CHLOROMETHYL-1,1-DIOXO-1,2-DIHYDRO-1LAMBDA*6*-BENZO[D]ISOTHIAZOL-3-ONE targets the Neutrophil elastase (human).
Chemical Properties
Molecular Weight231.66
FormulaC8H6ClNO3S
Cas No.13947-21-2
SmilesO=C1C=2C(S(=O)(=O)N1CCl)=CC=CC2
Relative Density.1.596g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 27.5 mg/mL (118.71 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM4.3167 mL21.5834 mL43.1667 mL215.8335 mL
5 mM0.8633 mL4.3167 mL8.6333 mL43.1667 mL
10 mM0.4317 mL2.1583 mL4.3167 mL21.5834 mL
20 mM0.2158 mL1.0792 mL2.1583 mL10.7917 mL
50 mM0.0863 mL0.4317 mL0.8633 mL4.3167 mL
100 mM0.0432 mL0.2158 mL0.4317 mL2.1583 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

SerineProteaseSerine ProteaseNeutrophil elastase (human)2CHLOROMETHYL1,1DIOXO1,2DIHYDRO1LAMBDA*6*BENZO[D]ISOTHIAZOL3ONE2 CHLOROMETHYL 1,1 DIOXO 1,2 DIHYDRO 1LAMBDA*6* BENZO[D]ISOTHIAZOL 3 ONE
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