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Refanezumab
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Catalog No. T77388Cas No. 1233953-61-1
Alias GSK249320, GSK 249320
Refanezumab (GSK249320) is an IgG1 humanized monoclonal antibody that crosses the blood-brain barrier (BBB) and targets myelin-associated glycoprotein (MAG) for the study of neurological and cardiovascular diseases.
Refanezumab
Refanezumab
😃Good
Catalog No. T77388Alias GSK249320, GSK 249320Cas No. 1233953-61-1
Refanezumab (GSK249320) is an IgG1 humanized monoclonal antibody that crosses the blood-brain barrier (BBB) and targets myelin-associated glycoprotein (MAG) for the study of neurological and cardiovascular diseases.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $450 | - | In Stock | |
| 5 mg | $1,400 | - | In Stock | |
| 10 mg | $2,220 | - | In Stock | |
| 25 mg | $4,210 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.2% (SDS-PAGE); 98.7% (SEC-HPLC)
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| Description | Refanezumab (GSK249320) is an IgG1 humanized monoclonal antibody that crosses the blood-brain barrier (BBB) and targets myelin-associated glycoprotein (MAG) for the study of neurological and cardiovascular diseases. |
| In vivo | Male Sprague Dawley rats were administered 10 mg/kg Refanezumab intravenously starting 24 hours after stroke onset and repeated weekly for a total of 6 doses. The results showed that this treatment resulted in significant improvements in neurologic scores and step tests. Refanezumab was able to penetrate the damaged area and had some positive impact on functional recovery within 24 hours of stroke. [1] |
| Synonyms | GSK249320, GSK 249320 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Siglec-4a/MAG |
| Molecular Weight | 148.28 kDa |
| Cas No. | 1233953-61-1 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | store at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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