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Refanezumab (Synonyms: GSK249320, GSK 249320)
Catalog No. T77388 Copy Product Info
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Refanezumab (GSK249320) is an IgG1 humanized monoclonal antibody that crosses the blood-brain barrier (BBB) and targets myelin-associated glycoprotein (MAG) for the study of neurological and cardiovascular diseases.
Refanezumab
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Catalog No. T77388
Synonyms GSK249320, GSK 249320
Refanezumab (GSK249320) is an IgG1 humanized monoclonal antibody that crosses the blood-brain barrier (BBB) and targets myelin-associated glycoprotein (MAG) for the study of neurological and cardiovascular diseases.
Refanezumab
Cas No. 1233953-61-1
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $450 | - | In Stock | |
| 5 mg | $1,400 | - | In Stock | |
| 10 mg | $2,220 | - | In Stock | |
| 25 mg | $4,210 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.2% (SDS-PAGE); 98.7% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Refanezumab (GSK249320) is an IgG1 humanized monoclonal antibody that crosses the blood-brain barrier (BBB) and targets myelin-associated glycoprotein (MAG) for the study of neurological and cardiovascular diseases. |
| In vivo | Male Sprague Dawley rats were administered 10 mg/kg Refanezumab intravenously starting 24 hours after stroke onset and repeated weekly for a total of 6 doses. The results showed that this treatment resulted in significant improvements in neurologic scores and step tests. Refanezumab was able to penetrate the damaged area and had some positive impact on functional recovery within 24 hours of stroke. [1] |
| Synonyms | GSK249320, GSK 249320 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | Siglec-4a/MAG |
| Molecular Weight | 148.28 kDa |
| Cas No. | 1233953-61-1 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature | Shipping with blue ice/Shipping at ambient temperature. |
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