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JTV-519 fumarate

Name: JTV-519 fumarate
Brand: TargetMol
SKU: T37807
Rating: 4.5 (1 reviews)

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Catalog No. T37807Cas No. 1883549-36-7

JTV-519 fumarate (K201 fumarate) is a SERCA blocker and partial agonist at the ryanodine receptor with antiarrhythmic and cardioprotective effects, improves sarcoplasmic reticulum calcium leakage, and may be useful in the study of anxiety disorders.

JTV-519 fumarate

😃Good

Catalog No. T37807Cas No. 1883549-36-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$146	6-8 weeks	6-8 weeks
5 mg	$359	6-8 weeks	6-8 weeks
10 mg	$533	6-8 weeks	6-8 weeks
25 mg	$863	6-8 weeks	6-8 weeks
50 mg	$1,190	6-8 weeks	6-8 weeks
100 mg	$1,580	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	540.67
Formula	C₂₉H₃₆N₂O₆S
Cas No.	1883549-36-7

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 54.07 mg/mL (100.01 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8496 mL	9.2478 mL	18.4956 mL	92.4779 mL
5 mM	0.3699 mL	1.8496 mL	3.6991 mL	18.4956 mL
10 mM	0.1850 mL	0.9248 mL	1.8496 mL	9.2478 mL
20 mM	0.0925 mL	0.4624 mL	0.9248 mL	4.6239 mL
50 mM	0.0370 mL	0.1850 mL	0.3699 mL	1.8496 mL
100 mM	0.0185 mL	0.0925 mL	0.1850 mL	0.9248 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc