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Antibacterial agent 42

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Catalog No. T38867Cas No. 1426572-47-5

Antibacterial Agent 42 demonstrates potent antibacterial activity by effectively reducing the Minimum Inhibitory Concentration (MIC) of the broad-spectrum antibacterial agent Ceftazidime.

Antibacterial agent 42

Antibacterial agent 42

😃Good
Catalog No. T38867Cas No. 1426572-47-5
Antibacterial Agent 42 demonstrates potent antibacterial activity by effectively reducing the Minimum Inhibitory Concentration (MIC) of the broad-spectrum antibacterial agent Ceftazidime.
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Product Introduction

Bioactivity
Description
Antibacterial Agent 42 demonstrates potent antibacterial activity by effectively reducing the Minimum Inhibitory Concentration (MIC) of the broad-spectrum antibacterial agent Ceftazidime.
In vitro
Antibacterial agent 42, as highlighted in example 5, substantially reduces the Minimum Inhibitory Concentration (MIC) values for Ceftazidime across various E. coli strains: NCTC 13351 (MIC=0.5 mcg/ml), M50 (MIC=1 mcg/ml), and 7MP (MIC=2 mcg/ml), demonstrating its efficacy in enhancing the antibiotic's effectiveness against these bacteria [1]. This information is derived from WO2013030735A1, example 5.
Chemical Properties
Molecular Weight380.29
FormulaC11H11N5NaO7S
Cas No.1426572-47-5
Smiles[Na].[H][C@]12CN([C@@H](CC1)c1nnc(o1)-c1ccon1)C(=O)N2OS(O)(=O)=O |TLB:21:20:5.6.7:3,8:5:3:18.20|jcExt:v:0:0
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Antibacterial agent 42
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