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Anti-FGF19 Antibody (1A6)

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Catalog No. T9901A-1351
Alias 1A6

Anti-FGF19 Antibody (1A6) represents a highly specialized monoclonal antibody specifically engineered to target the human fibroblast growth factor 19 with exceptional binding affinity. It effectively facilitates the measurable neutralization of FGF19-mediated signaling across various preclinical experimental models to evaluate the blockade of the FGFR4/beta-Klotho complex during strictly monitored laboratory observation periods and functional cell signaling assays to ensure high experimental sensitivity in molecular oncology.

Anti-FGF19 Antibody (1A6)

Anti-FGF19 Antibody (1A6)

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Catalog No. T9901A-1351Alias 1A6
Anti-FGF19 Antibody (1A6) represents a highly specialized monoclonal antibody specifically engineered to target the human fibroblast growth factor 19 with exceptional binding affinity. It effectively facilitates the measurable neutralization of FGF19-mediated signaling across various preclinical experimental models to evaluate the blockade of the FGFR4/beta-Klotho complex during strictly monitored laboratory observation periods and functional cell signaling assays to ensure high experimental sensitivity in molecular oncology.
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Product Introduction

Bioactivity
Description
Anti-FGF19 Antibody (1A6) represents a highly specialized monoclonal antibody specifically engineered to target the human fibroblast growth factor 19 with exceptional binding affinity. It effectively facilitates the measurable neutralization of FGF19-mediated signaling across various preclinical experimental models to evaluate the blockade of the FGFR4/beta-Klotho complex during strictly monitored laboratory observation periods and functional cell signaling assays to ensure high experimental sensitivity in molecular oncology.
In vitro
In human hepatocellular carcinoma cell lines (e.g., Hep3B), Anti-FGF19 Antibody (1A6) blocked FGF19-induced FGFR4 autophosphorylation and suppressed colony formation [1].
In vivo
In human hepatocellular carcinoma xenograft models and FGF19 transgenic mice, systemic administration of Anti-FGF19 Antibody (1A6) significantly inhibited tumor growth [1].
Synonyms1A6
Clone
1A6
Reactivity
Human
Application
FACS
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Uniprot ID
TargetFGF19
Chemical Properties
Antibody Information
IsotypeIgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

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