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Anti-FGF19 Antibody (1A6)
(Synonyms: 1A6) Copy Product Info
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Synonyms: 1A6
Catalog No. T9901A-1351 Copy Product Info
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Anti-FGF19 Antibody (1A6) represents a highly specialized monoclonal antibody specifically engineered to target the human fibroblast growth factor 19 with exceptional binding affinity. It effectively facilitates the measurable neutralization of FGF19-mediated signaling across various preclinical experimental models to evaluate the blockade of the FGFR4/beta-Klotho complex during strictly monitored laboratory observation periods and functional cell signaling assays to ensure high experimental sensitivity in molecular oncology.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-FGF19 Antibody (1A6) represents a highly specialized monoclonal antibody specifically engineered to target the human fibroblast growth factor 19 with exceptional binding affinity. It effectively facilitates the measurable neutralization of FGF19-mediated signaling across various preclinical experimental models to evaluate the blockade of the FGFR4/beta-Klotho complex during strictly monitored laboratory observation periods and functional cell signaling assays to ensure high experimental sensitivity in molecular oncology. |
| In vitro | In human hepatocellular carcinoma cell lines (e.g., Hep3B), Anti-FGF19 Antibody (1A6) blocked FGF19-induced FGFR4 autophosphorylation and suppressed colony formation [1]. |
| In vivo | In human hepatocellular carcinoma xenograft models and FGF19 transgenic mice, systemic administration of Anti-FGF19 Antibody (1A6) significantly inhibited tumor growth [1]. |
| Synonyms | 1A6 |
| Clone | 1A6 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | FGF19 |
| Isotype | IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Anti-FGF19 Antibody (1A6) chemical structure | Anti-FGF19 Antibody (1A6) in vivo | Anti-FGF19 Antibody (1A6) in vitro
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