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FITC-Dextran (MW 70000)

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Catalog No. T212693

FITC-Dextran (MW 70000) is a compound categorized under fluorescent dyes. It is commonly used as a tracer molecule in biomedical research to label and track cells or other biological substances. Composed of fluorescein isothiocyanate (FITC) and dextran—a complex carbohydrate extracted from starch—this combination forms a stable fluorescent tracer, which can be observed under a microscope or quantified using specialized detection equipment.

FITC-Dextran (MW 70000)
Other Forms of FITC-Dextran (MW 70000):

FITC-Dextran (MW 70000)

😃Good
Catalog No. T212693
FITC-Dextran (MW 70000) is a compound categorized under fluorescent dyes. It is commonly used as a tracer molecule in biomedical research to label and track cells or other biological substances. Composed of fluorescein isothiocyanate (FITC) and dextran—a complex carbohydrate extracted from starch—this combination forms a stable fluorescent tracer, which can be observed under a microscope or quantified using specialized detection equipment.
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Product Introduction

Bioactivity
Description
FITC-Dextran (MW 70000) is a compound categorized under fluorescent dyes. It is commonly used as a tracer molecule in biomedical research to label and track cells or other biological substances. Composed of fluorescein isothiocyanate (FITC) and dextran—a complex carbohydrate extracted from starch—this combination forms a stable fluorescent tracer, which can be observed under a microscope or quantified using specialized detection equipment.
In vitro
FITC-Dextran (MW 70000) is a fluorescein isothiocyanate (FITC) dextran fluorescent probe (Ex=495 nm; Em=525 nm). It serves as a marker to reveal cell damage induced by heat shock and to study the early and late stages of apoptosis. Additionally, FITC-Dextran (MW 70000) is used in research on cell permeability, such as evaluating blood-brain barrier permeability and the extent of its disruption. Storage instructions: protect from light.
In vivo
To assess intestinal barrier function: 1. Subject mice to a 4-hour fasting period. 2. Administer FITC-Dextran MW 70000 orally to the mice at a dosage of 0.6 mg/g. 3. Measure fluorescence intensity within 4 hours (Ex nm/Em 520 nm).
Chemical Properties
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Stock solution preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (stock solution concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
The above example illustrates how to use "In Vivo Formulation Calculator" and does not represent a recommended formulation for any specific compound. Please select an appropriate dissolution method based on your experimental animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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