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1-Methyl-1,2,3,4-tetrahydroisoquinoline

Name: 1-Methyl-1,2,3,4-tetrahydroisoquinoline
Brand: TargetMol
SKU: TN9617
Rating: 4.5 (1 reviews)

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Catalog No. TN9617Cas No. 4965-09-7

1-Methyl-1,2,3,4-tetrahydroisoquinoline is an inhibitor of phenylethanolamine N-methyltransferase and can be used in biochemical experiments and drug synthesis.

1-Methyl-1,2,3,4-tetrahydroisoquinoline

🥰Excellent

Catalog No. TN9617Cas No. 4965-09-7

1-Methyl-1,2,3,4-tetrahydroisoquinoline is an inhibitor of phenylethanolamine N-methyltransferase and can be used in biochemical experiments and drug synthesis.

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Product Introduction

Bioactivity

Description	1-Methyl-1,2,3,4-tetrahydroisoquinoline is an inhibitor of phenylethanolamine N-methyltransferase and can be used in biochemical experiments and drug synthesis.
In vivo	Methods: STZ-induced diabetic mice were treated with 1-Methyl-1,2,3,4-tetrahydroisoquinoline (15, 30, 45 mg/kg, intraperitoneal injection) to study its effects on STZ-induced diabetic static mechanical allodynia. Results: The highest dose of 1-Methyl-1,2,3,4-tetrahydroisoquinoline (45 mg/kg) induced a more significant reversal of DPN allodynia 30 minutes after administration. [1]

Chemical Properties

Molecular Weight	147.22
Formula	C₁₀H₁₃N
Cas No.	4965-09-7
Smiles	C=1C=CC2=C(C1)CCNC2C

Storage & Solubility Information

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store under nitrogen,keep away from direct sunlight | store at 4°C | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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