Angiogenin Fragment (108-123) acetate is the C-terminal fragment 108-123 of angiogenin, inhibiting both its enzymatic and biological activities.

Angiogenin Fragment (108-123) acetate can inhibit the initial degradation rate of tRNA catalyzed by angiogenin in a concentration-dependent manner, with a Ki value of 278 μM. When tRNA is used as the reaction substrate, Angiogenin Fragment (108-123) acetate can also suppress the nuclease activity of angiogenin. Furthermore, in the chick chorioallantoic membrane assay, Angiogenin Fragment (108-123) acetate significantly attenuates angiogenin-induced neovascularization [1].