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Benzylthiouracil (6-Benzyl-2-thiouracil) induces ANCA-associated glomerulonephritis in Graves' disease patients and is used to study hyperthyroidism.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $40 | In Stock | In Stock | |
| 50 mg | $64 | In Stock | In Stock | |
| 100 mg | $95 | In Stock | In Stock | |
| 500 mg | $218 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $44 | In Stock | In Stock |
| Description | Benzylthiouracil (6-Benzyl-2-thiouracil) induces ANCA-associated glomerulonephritis in Graves' disease patients and is used to study hyperthyroidism. |
| In vivo | In rats, Benzylthiouracil was observed to be ten times more potent than thiouracil and methylthiouracil in inhibiting the thyroid's ability to naturally collect iodine, but there was no significant difference in the duration of inhibition at the smallest effective dose. [1] |
| Synonyms | 6-Benzyl-2-thiouracil |
| Molecular Weight | 218.28 |
| Formula | C11H10N2OS |
| Cas No. | 6336-50-1 |
| Smiles | O=C1C=C(NC(=S)N1)CC=2C=CC=CC2 |
| Storage | store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 180 mg/mL (824.63 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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