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(E)-Aztreonam (SQ-28429) is a monocyclic beta-lactam antibiotic with activity against gram-negative pathogens. (E)-Aztreonam represents a valuable research compound for studying bacterial infections and therapeutic strategies against resistant gram-negative organisms.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $158 | - | In Stock | |
| 5 mg | $396 | - | In Stock | |
| 10 mg | $635 | - | In Stock | |
| 25 mg | $983 | - | In Stock | |
| 50 mg | $1,320 | - | In Stock |
| Description | (E)-Aztreonam (SQ-28429) is a monocyclic beta-lactam antibiotic with activity against gram-negative pathogens. (E)-Aztreonam represents a valuable research compound for studying bacterial infections and therapeutic strategies against resistant gram-negative organisms. |
| In vivo | (E)-Aztreonam (28 mg/kg, once daily for 14 consecutive days) was intraperitoneally injected into mice, resulting in increased activation of peritoneal cells and enhanced IL-1 production capacity by macrophages. [3] |
| Synonyms | SQ-28429, SQ 28429, Aztreonam E-isomer |
| Molecular Weight | 435.43 |
| Formula | C13H17N5O8S2 |
| Cas No. | 99341-02-3 |
| Smiles | N(C(/C(=N/OC(C(O)=O)(C)C)/C1=CSC(N)=N1)=O)[C@H]2[C@H](C)N(S(=O)(=O)O)C2=O |
| Relative Density. | 1.31g/cm3 |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO: ≥ 80 mg/mL, Sonication is recommended. |
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (7.58 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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