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Cholesterol-d6

Name: Cholesterol-d6
Brand: TargetMol
SKU: TMID-0224
Rating: 4.5 (1 reviews)

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Catalog No. TMID-0224Cas No. 60816-17-3

Cholesterol-d6 is a deuterated chlosterol that can be used to study lipid membrane flow and chlosterol metabolism in vivo.

Cholesterol-d6

😃Good

Catalog No. TMID-0224Cas No. 60816-17-3

Cholesterol-d6 is a deuterated chlosterol that can be used to study lipid membrane flow and chlosterol metabolism in vivo.

Pack Size	Price	Availability
1 mg	$223	6-8 weeks
5 mg	$555	6-8 weeks
10 mg	$798	6-8 weeks

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Product Introduction

Bioactivity

Description	Cholesterol-d6 is a deuterated chlosterol that can be used to study lipid membrane flow and chlosterol metabolism in vivo.
In vitro	In some cases, deuterated compounds may have advantages over nondeuterated forms, often by altering interstitial properties. Deuteration may also redirect metabolic pathways in a direction that reduces toxicity.[1]

Chemical Properties

Molecular Weight	392.69
Formula	C₂₇H₄₀D₆O
Cas No.	60816-17-3
Smiles	C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C([2H])([2H])[2H])C([2H])([2H])[2H])C)[H])[H]
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 15 mg/mL (38.20 mM), Sonication is recommended.

DMSO: 1 mg/mL (2.55 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO/Ethanol

	1mg	5mg	10mg	50mg
1 mM	2.5465 mL	12.7327 mL	25.4654 mL	127.3269 mL

Ethanol

	1mg	5mg	10mg	50mg
5 mM	0.5093 mL	2.5465 mL	5.0931 mL	25.4654 mL
10 mM	0.2547 mL	1.2733 mL	2.5465 mL	12.7327 mL
20 mM	0.1273 mL	0.6366 mL	1.2733 mL	6.3663 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc