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Glycoursodeoxycholic Acid-d4 (Synonyms: Ursodeoxycholylglycine-d4)

Name: Glycoursodeoxycholic Acid-d4
Brand: TargetMol
SKU: TMIH-0257
Rating: 4.5 (1 reviews)

Catalog No. TMIH-0257 Copy Product Info

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Glycoursodeoxycholic Acid-D4 is a deuterated compound of Glycoursodeoxycholic Acid. Glycoursodeoxycholic Acid (T5234) has a CAS number of 64480-66-6. Glycoursodeoxycholic acid is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment. In hepatocytes, both primary and secondary bile acids undergo amino acid conjugation at the C-24 carboxylic acid on the side chain, and almost all bile acids in the bile duct, therefore, exist in a glycine conjugated form. Bile acids are steroid acids found predominantly in bile of mammals.

Glycoursodeoxycholic Acid-d4

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Catalog No. TMIH-0257

Synonyms Ursodeoxycholylglycine-d4

Cas No. 2044276-17-5

Pack Size	Price	USA Stock	Global Stock
10 mg	$457	7-10 days	7-10 days
25 mg	$845	7-10 days	7-10 days
50 mg	$1,430	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Appearance:Solid

Color:White

Resource Download

COA

Product Introduction

Bioactivity

Description

Synonyms

Ursodeoxycholylglycine-d4

Chemical Properties

Molecular Weight	453.65
Formula	C₂₆H₄₃NO₅
Cas No.	2044276-17-5
Smiles	C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](C[C@@H]3O)(C([C@H](O)C(C4)([2H])[2H])([2H])[2H])[H])(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(NCC(O)=O)=O)C)[H])[H]

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (220.43 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2043 mL	11.0217 mL	22.0434 mL	110.2171 mL
5 mM	0.4409 mL	2.2043 mL	4.4087 mL	22.0434 mL
10 mM	0.2204 mL	1.1022 mL	2.2043 mL	11.0217 mL
20 mM	0.1102 mL	0.5511 mL	1.1022 mL	5.5109 mL
50 mM	0.0441 mL	0.2204 mL	0.4409 mL	2.2043 mL
100 mM	0.0220 mL	0.1102 mL	0.2204 mL	1.1022 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

Citations

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

64480-66-6