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Atorvastatin calcium hydrate

Name: Atorvastatin calcium hydrate
Brand: TargetMol
SKU: T21363
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Di(CI-981) calcium trihydrate, Di(Atorvastatin) calcium trihydrate, CI 981 calcium hydrate) Copy Product Info

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Synonyms: Di(CI-981) calcium trihydrate, Di(Atorvastatin) calcium trihydrate, CI 981 calcium hydrate

Catalog No. T21363 Copy Product Info

Purity: 99.97%

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Atorvastatin calcium hydrate is an oral lipid-lowering compound belonging to the class of HMG-CoA reductase inhibitors. Atorvastatin calcium hydrate significantly reduces serum LDL cholesterol levels by inhibiting a key enzyme involved in cholesterol biosynthesis. Atorvastatin calcium hydrate is used in in vitro experiments to study cholesterol metabolism, lipid accumulation, and the regulation of related signaling pathways, and is commonly employed in high-fat diet animal models to validate its lipid-lowering effects.

Cas No. 344423-98-9

Pack Size	Price	USA Stock	Global Stock
50 mg	$31	-	In Stock
100 mg	$48	-	In Stock
500 mg	$147	-	In Stock
1 mL x 10 mM (in DMSO)	$35	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:99.97%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Synonyms

Di(CI-981) calcium trihydrate, Di(Atorvastatin) calcium trihydrate, CI 981 calcium hydrate

Chemical Properties

Molecular Weight	605.72
Formula	C₃₃H₃₅FN₂O₅.1/2Ca.3/2H₂O
Cas No.	344423-98-9
Smiles	O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(C=C2)F)=C1C3=CC=CC=C3)NC4=CC=CC=C4.O=C(C5=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C6=CC=C(C=C6)F)=C5C7=CC=CC=C7)NC8=CC=CC=C8.O.O.O.[Ca+2]
Relative Density.	no data available

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: Insoluble

DMSO: 80 mg/mL (132.07 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.6509 mL	8.2546 mL	16.5093 mL	82.5464 mL
5 mM	0.3302 mL	1.6509 mL	3.3019 mL	16.5093 mL
10 mM	0.1651 mL	0.8255 mL	1.6509 mL	8.2546 mL
20 mM	0.0825 mL	0.4127 mL	0.8255 mL	4.1273 mL
50 mM	0.0330 mL	0.1651 mL	0.3302 mL	1.6509 mL
100 mM	0.0165 mL	0.0825 mL	0.1651 mL	0.8255 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc