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TREM2 agonist-3
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Catalog No. T210639
TREM2 agonist-3 (Compound 4i) is a TREM2 agonist with a KD value of 19.0 µM and a KD value of 39.8 µM for TREM1. It can induce increased phosphorylation levels of SYK and is applicable for research into neurodegenerative diseases and other conditions associated with TREM2 dysfunction.
TREM2 agonist-3
TREM2 agonist-3
😃Good
Catalog No. T210639
TREM2 agonist-3 (Compound 4i) is a TREM2 agonist with a KD value of 19.0 µM and a KD value of 39.8 µM for TREM1. It can induce increased phosphorylation levels of SYK and is applicable for research into neurodegenerative diseases and other conditions associated with TREM2 dysfunction.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
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Chemical Properties
| Description | TREM2 agonist-3 (Compound 4i) is a TREM2 agonist with a KD value of 19.0 µM and a KD value of 39.8 µM for TREM1. It can induce increased phosphorylation levels of SYK and is applicable for research into neurodegenerative diseases and other conditions associated with TREM2 dysfunction. |
| Targets&IC50 | TREM2:19.0 μM (Kd) |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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