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ASN04885796

Name: ASN04885796
Brand: TargetMol
SKU: T30163
Price: 61 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T30163Cas No. 1032892-26-4

Alias AS-N04885796, ASN 04885796, AS N04885796

ASN04885796 (compound IV) is a neuroprotective, specific GPR17 agonist with an EC50=2.27 nM for GPR17-mediated GTPγS binding and can be used to study neurodegenerative diseases such as cerebral ischemia and demyelinating diseases.

ASN04885796

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Purity: 95.36%

Catalog No. T30163Alias AS-N04885796, ASN 04885796, AS N04885796Cas No. 1032892-26-4

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$61	-	In Stock
5 mg	$147	-	In Stock
10 mg	$239	-	In Stock
25 mg	$395	-	In Stock
50 mg	$588	-	In Stock
100 mg	$838	-	In Stock
200 mg	$1,130	-	In Stock
1 mL x 10 mM (in DMSO)	$168	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:95.36%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	ASN04885796 (compound IV) is a neuroprotective, specific GPR17 agonist with an EC50=2.27 nM for GPR17-mediated GTPγS binding and can be used to study neurodegenerative diseases such as cerebral ischemia and demyelinating diseases.
Targets&IC50	GTPγS binding assay:2.27 nM (EC₅₀)
In vitro	ASN04885796 (compound IV) is a potent GPR17 agonist, exhibiting an EC₅₀ of 2.27 nM in assays measuring GTPγS binding stimulated by GPR17. ASN04885796 possesses neuroprotective effects and serves as a valuable tool for studying neurological disorders[1].
Synonyms	AS-N04885796, ASN 04885796, AS N04885796

Chemical Properties

Molecular Weight	517.55
Formula	C₂₈H₂₈FN₅O₄
Cas No.	1032892-26-4
Smiles	O=C(NCC1OCCC1)C(C2=CC=C(F)C=C2)N(C(=O)CN3N=NC=4C=CC=CC43)C5=CC=C(OC)C=C5
Relative Density.	1.34 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (154.57 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 3.3 mg/mL (6.38 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9322 mL	9.6609 mL	19.3218 mL	96.6090 mL
5 mM	0.3864 mL	1.9322 mL	3.8644 mL	19.3218 mL
10 mM	0.1932 mL	0.9661 mL	1.9322 mL	9.6609 mL
20 mM	0.0966 mL	0.4830 mL	0.9661 mL	4.8305 mL
50 mM	0.0386 mL	0.1932 mL	0.3864 mL	1.9322 mL
100 mM	0.0193 mL	0.0966 mL	0.1932 mL	0.9661 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc