Anti-RSPO1 Antibody is a specific monoclonal antibody targeting R-spondin-1 (RSPO1), a potent activator of the Wnt/beta-catenin signaling pathway. RSPO1 enhances signaling by binding to LGR4/5/6 receptors. This antibody specifically neutralizes RSPO1 and blocks its-mediated signal activation, serving as a vital tool for studying stem cell proliferation, intestinal crypt maintenance, and the progression of Wnt-dependent tumors.