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6-Thioguanosine

Name: 6-Thioguanosine
Brand: TargetMol
SKU: T20511
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T20511Cas No. 85-31-4

Alias NSC-29422, NSC29422, NSC 29422, 6-Mercaptoguanosine

6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside, a metabolite of Azathioprine, and a low molecular weight gel.6-Thioguanosine is immunosuppressive and has been used to study the formation of the RNA double helix.

6-Thioguanosine

🥰Excellent

Purity: 98%

Catalog No. T20511Alias NSC-29422, NSC29422, NSC 29422, 6-MercaptoguanosineCas No. 85-31-4

Pack Size	Price	Availability	Quantity
100 mg	$35	In Stock
1 mL x 10 mM (in DMSO)	$39	In Stock

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Purity:98%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside, a metabolite of Azathioprine, and a low molecular weight gel.6-Thioguanosine is immunosuppressive and has been used to study the formation of the RNA double helix.
Synonyms	NSC-29422, NSC29422, NSC 29422, 6-Mercaptoguanosine

Chemical Properties

Molecular Weight	299.31
Formula	C₁₀H₁₃N₅O₄S
Cas No.	85-31-4
Smiles	Nc1nc2n(cnc2c(=S)[nH]1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Relative Density.	2.18 g/cm3
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 6.88 mg/mL (22.97 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3410 mL	16.7051 mL	33.4102 mL	167.0509 mL
5 mM	0.6682 mL	3.3410 mL	6.6820 mL	33.4102 mL
10 mM	0.3341 mL	1.6705 mL	3.3410 mL	16.7051 mL
20 mM	0.1671 mL	0.8353 mL	1.6705 mL	8.3525 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc