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4-Hydroxyhygric acid

Catalog No. T66665 Copy Product Info
Purity: 99.98%
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4-Hydroxyhygric acid is a unique non-protein imino acid (a proline analogue) isolated from the leaves of five species of the tropical leguminous tree Copaifera. It serves as a key chemical defense metabolite for the plant. Studies have demonstrated that it functions as a potent inhibitor of larval development in the seed-feeding bruchid beetle Callosobruchus maculatus and exhibits significant feeding deterrence against the leaf-feeding lepidopteran Spodoptera littoralis. By modulating insect growth and behavior, it acts as a natural biopesticide within the tropical forest ecosystem.

4-Hydroxyhygric acid

Copy Product Info
😃Good
Catalog No. T66665

4-Hydroxyhygric acid is a unique non-protein imino acid (a proline analogue) isolated from the leaves of five species of the tropical leguminous tree Copaifera. It serves as a key chemical defense metabolite for the plant. Studies have demonstrated that it functions as a potent inhibitor of larval development in the seed-feeding bruchid beetle Callosobruchus maculatus and exhibits significant feeding deterrence against the leaf-feeding lepidopteran Spodoptera littoralis. By modulating insect growth and behavior, it acts as a natural biopesticide within the tropical forest ecosystem.

4-Hydroxyhygric acid
Cas No. 4252-82-8
TargetMol
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Batch Information

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Purity:99.98%
Appearance:Solid
Color:Yellow to Brown
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
4-Hydroxyhygric acid is a unique non-protein imino acid (a proline analogue) isolated from the leaves of five species of the tropical leguminous tree Copaifera. It serves as a key chemical defense metabolite for the plant. Studies have demonstrated that it functions as a potent inhibitor of larval development in the seed-feeding bruchid beetle Callosobruchus maculatus and exhibits significant feeding deterrence against the leaf-feeding lepidopteran Spodoptera littoralis. By modulating insect growth and behavior, it acts as a natural biopesticide within the tropical forest ecosystem.
Chemical Properties
Molecular Weight145.16
FormulaC6H11NO3
Cas No.4252-82-8
SmilesC(O)(=O)[C@@H]1C[C@@H](O)CN1C
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 2.00 mg/mL (13.78 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.8890 mL34.4448 mL68.8895 mL344.4475 mL
5 mM1.3778 mL6.8890 mL13.7779 mL68.8895 mL
10 mM0.6889 mL3.4445 mL6.8890 mL34.4448 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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