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Fmoc-Tyr(tBu)-OH is a protected amino acid derivative widely employed in Fmoc-based solid-phase peptide synthesis and serves as a key reagent for the stepwise assembly of peptide chains. Fmoc-Tyr(tBu)-OH can be specifically utilized to synthesize Leu-EnkephalinAmide through solid-phase synthesis in aqueous media and is also used for the generation of amino acid derivatives such as Fmoc-Tyr-OAllyl, highlighting its versatility and importance in peptide chemistry.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 g | $29 | - | In Stock |
| Description | Fmoc-Tyr(tBu)-OH is a protected amino acid derivative widely employed in Fmoc-based solid-phase peptide synthesis and serves as a key reagent for the stepwise assembly of peptide chains. Fmoc-Tyr(tBu)-OH can be specifically utilized to synthesize Leu-EnkephalinAmide through solid-phase synthesis in aqueous media and is also used for the generation of amino acid derivatives such as Fmoc-Tyr-OAllyl, highlighting its versatility and importance in peptide chemistry. |
| In vitro | Fmoc-Tyr(tBu)-OH is highly valuable in peptide chemistry for synthesizing complex peptides and proteins for research. |
| Molecular Weight | 459.54 |
| Formula | C28H29NO5 |
| Cas No. | 71989-38-3 |
| Smiles | C(OC(N[C@@H](CC1=CC=C(OC(C)(C)C)C=C1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3 |
| Sequence | Fmoc-Tyr(tBu)-OH |
| Sequence Short | X |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (174.09 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (7.18 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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