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Bunaftide

Name: Bunaftide
Brand: TargetMol
SKU: T10634
Price: 167 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T10634Cas No. 32421-46-8

Alias Meregon, Bunaphtide, Bunaftine

Bunaftide (Bunaphtid) has antiarrhythmic effects and inhibits aconitine-induced ventricular tachycardia.

Bunaftide

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Purity: 99.16%

Catalog No. T10634Alias Meregon, Bunaphtide, BunaftineCas No. 32421-46-8

Bunaftide (Bunaphtid) has antiarrhythmic effects and inhibits aconitine-induced ventricular tachycardia.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$167	-	In Stock
5 mg	$407	-	In Stock
10 mg	$541	-	In Stock
25 mg	$819	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.16%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Bunaftide (Bunaphtid) has antiarrhythmic effects and inhibits aconitine-induced ventricular tachycardia.
In vitro	Bunaftide (0.5-2.0 mM) causes contraction and rounding of the cells with loss of microvilli-like processes. 0.4 mM Bunaftide increases and 0.8-1.0 mM markedly decreases the percentage of mitotic cells, without accumulation of cells in any particular stage of mitosis.[1] Bunaftide (1, 5, and 10 mg/L) produces a concentration-dependent depression of the maximum rate of rising of the action potential in guinea pig papillary muscle preparations without affecting the resting membrane potential and the action potential amplitude. The action potential duration (APD50, APD90) is significantly prolonged by the treatment with 1 and 5 mg/L Bunaftide, while it is not changed by the treatment with 10 mg/L.[2]
Synonyms	Meregon, Bunaphtide, Bunaftine

Chemical Properties

Molecular Weight	326.48
Formula	C₂₁H₃₀N₂O
Cas No.	32421-46-8
Smiles	C(N(CCN(CC)CC)CCCC)(=O)C=1C2=C(C=CC1)C=CC=C2
Relative Density.	1.026g/cm3

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (183.78 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0630 mL	15.3149 mL	30.6297 mL	153.1487 mL
5 mM	0.6126 mL	3.0630 mL	6.1259 mL	30.6297 mL
10 mM	0.3063 mL	1.5315 mL	3.0630 mL	15.3149 mL
20 mM	0.1531 mL	0.7657 mL	1.5315 mL	7.6574 mL
50 mM	0.0613 mL	0.3063 mL	0.6126 mL	3.0630 mL
100 mM	0.0306 mL	0.1531 mL	0.3063 mL	1.5315 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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