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Oxadiazon is a protoporphyrinogen oxidase (PPO) inhibitor and herbicide that suppresses photosynthesis at the chloroplast level.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
500 mg | $40 | In Stock | |
1 g | $56 | In Stock | |
5 g | $133 | In Stock | |
10 g | $198 | In Stock | |
1 mL x 10 mM (in DMSO) | $39 | In Stock |
Description | Oxadiazon is a protoporphyrinogen oxidase (PPO) inhibitor and herbicide that suppresses photosynthesis at the chloroplast level. |
In vitro | Methods: Oxadiazon (7.81 μM) was used to treat Homo sapiens striatal precursor (HSP) cells to investigate the neurotoxic effects of Oxadiazon on HSP cells. Results: Oxadiazon inhibited the gene and protein expression of ALDH2 as well as its enzymatic activity, while increasing the expression and activity of ACYP2. It also significantly suppressed FGF2- and BDNF-induced neuronal differentiation.[1] |
In vivo | Methods: Oxadiazon (20–500 mg/kg/day) was administered orally to male Sprague-Dawley rats to examine its ability to induce hepatic peroxisome proliferation. Results: Oxadiazon significantly increased liver weight and the liver-to-body weight ratio in rats, while promoting peroxisome proliferation and raising enzyme activity. [2] |
Molecular Weight | 345.22 |
Formula | C15H18Cl2N2O3 |
Cas No. | 19666-30-9 |
Smiles | CC(C)Oc1cc(c(Cl)cc1Cl)-n1nc(oc1=O)C(C)(C)C |
Relative Density. | 1.4130 g/cm3 (Estimated) |
Color | Yellow |
Appearance | Solid |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMSO: ≥ 40 mg/mL, Sonication is recommended. |
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