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ICG-amine

Name: ICG-amine
Brand: TargetMol
SKU: T39153
Price: 190 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T39153Cas No. 1686147-55-6

ICG-amine is a tricarbocyanine near-infrared fluorescent probe that binds efficiently to amino acid residues without requiring condensing agents.

ICG-amine

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Catalog No. T39153Cas No. 1686147-55-6

ICG-amine is a tricarbocyanine near-infrared fluorescent probe that binds efficiently to amino acid residues without requiring condensing agents.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$190	-	In Stock
5 mg	$531	-	In Stock
10 mg	$850	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Appearance:Solid

Color:Green

Resource Download

COA

Product Introduction

Bioactivity

Description	ICG-amine is a tricarbocyanine near-infrared fluorescent probe that binds efficiently to amino acid residues without requiring condensing agents.
In vitro	Using ICG-amine (Indocyanine Green) as the backbone, an amino (-NH₂) functional group was introduced through chemical modification. The ICG core contains a conjugated double bond system and an indole ring, conferring near-infrared fluorescence properties, while the amino group provides reactivity for covalent conjugation with carboxyl groups, NHS esters, aldehydes, etc.

Chemical Properties

Molecular Weight	829.16
Formula	C₅₁H₆₄N₄O₄S
Cas No.	1686147-55-6
Smiles	O=C(NCCCCCCN)CCCCCN1C=2C=CC=3C=CC=CC3C2C(C1=CC=CC=CC=CC4=[N+](C=5C=CC=6C=CC=CC6C5C4(C)C)CCCCS(=O)(=O)[O-])(C)C

Storage & Solubility Information

Storage

keep away from direct sunlight | store at -20°C | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 24 mg/mL (28.94 mM), Sonication is recommeded.

H2O: 4 mg/mL (4.82 mM), Sonication is recommeded.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.2060 mL	6.0302 mL	12.0604 mL	60.3020 mL

DMSO

	1mg	5mg	10mg	50mg
5 mM	0.2412 mL	1.2060 mL	2.4121 mL	12.0604 mL
10 mM	0.1206 mL	0.6030 mL	1.2060 mL	6.0302 mL
20 mM	0.0603 mL	0.3015 mL	0.6030 mL	3.0151 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ICG-amineICGamineICG amine