Fradafiban

Name: Fradafiban
Brand: TargetMol
SKU: T11322
Rating: 4.5 (1 reviews)

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Catalog No. T11322Cas No. 148396-36-5

Alias BIBU-52

Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.

Fradafiban

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Catalog No. T11322Alias BIBU-52Cas No. 148396-36-5

Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.

Pack Size	Price	Availability
25 mg	$1,820	10-14 weeks
50 mg	$2,380	10-14 weeks
100 mg	$3,100	10-14 weeks

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Product Introduction

Bioactivity

Description	Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.
Targets&IC50	GP IIb/IIIa complex (human platelet):(kd)148 nM
In vitro	Fradafiban binds with high affinity and selectivity to the human platelet GP IIb/IIIa complex and potently inhibits human platelet aggregation in vitro.?Fradafiban reversibly binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.?Fradafiban is a nonpeptide mimetic of the arginine-glycine-aspartic acid recognition sequence.
In vivo	Fradafiban exhibits limited oral activity, likely attributed to its high polarity, which results in poor absorption following oral ingestion.
Synonyms	BIBU-52

Chemical Properties

Molecular Weight	367.40
Formula	C₂₀H₂₁N₃O₄
Cas No.	148396-36-5
Relative Density.	1.38g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

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Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

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mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

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