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Thozalinone

Name: Thozalinone
Brand: TargetMol
SKU: T19893
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T19893Cas No. 655-05-0

Thozalinone is a psychostimulant agent inducing the release of norepinephrine and dopamine.

Thozalinone

🥰Excellent

Purity: 99.68%

Catalog No. T19893Cas No. 655-05-0

Thozalinone is a psychostimulant agent inducing the release of norepinephrine and dopamine.

Pack Size	Price	Availability
10 mg	$36	In Stock
25 mg	$64	In Stock
50 mg	$95	In Stock
100 mg	$143	In Stock
200 mg	$213	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.68%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Thozalinone is a psychostimulant agent inducing the release of norepinephrine and dopamine.
In vivo	In ICR male mice, Thozalinone (100 mg/kg, ip) test (SI) appear to provide the best prediction for the PS-inducing potencies among DL-DOPA, apomorphine, and amphetamine.

Chemical Properties

Molecular Weight	204.23
Formula	C₁₁H₁₂N₂O₂
Cas No.	655-05-0
Smiles	CN(C)C1=NC(=O)C(O1)c1ccccc1
Relative Density.	1.19 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (134.65 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8964 mL	24.4822 mL	48.9644 mL	244.8220 mL
5 mM	0.9793 mL	4.8964 mL	9.7929 mL	48.9644 mL
10 mM	0.4896 mL	2.4482 mL	4.8964 mL	24.4822 mL
20 mM	0.2448 mL	1.2241 mL	2.4482 mL	12.2411 mL
50 mM	0.0979 mL	0.4896 mL	0.9793 mL	4.8964 mL
100 mM	0.0490 mL	0.2448 mL	0.4896 mL	2.4482 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc