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Anti-Fc gamma R1 Antibody
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Catalog No. T9901A-1260 Copy Product Info
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Anti-Fc gamma R1 Antibody is a humanized monoclonal antibody that targets Fc gamma RI (CD64) and can be used in immunological research.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $377 | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Fc gamma R1 Antibody is a humanized monoclonal antibody that targets Fc gamma RI (CD64) and can be used in immunological research. |
| In vitro | Anti-Fc gamma R1 Antibody binds human CD64 on monocytes/neutrophils with high affinity. Targeting an epitope outside the Fc-binding pocket, it captures antigens even under IgG saturation and triggers rapid internalization for MHC-mediated presentation [1]. |
| In vivo | In transgenic mice expressing human FcγRI (CD64), systemic administration of antigen conjugated to Anti-Fc gamma R1 Antibody increases specific antibody production 100-1000 fold compared to non-targeted antigens. This treatment significantly raises antigen-specific IgG and IgM titers, confirming that targeting CD64 on myeloid cells bypasses immune clearance and promotes potent humoral immunity [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | FcgammaR1 |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Anti-Fc gamma R1 Antibody chemical structure | Anti-Fc gamma R1 Antibody in vivo | Anti-Fc gamma R1 Antibody in vitro
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