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5-ALA benzyl ester hydrochloride (Benzyl-ALA hydrochloride) is a protoporphyrin precursor used as a photodetection agent. It induces protoporphyrin IX (PPIX) accumulation in colon carcinoma cell lines.

Fmoc-Ala-Ala-Asn(Trt)-OH, a cleavable linker essential in ADC (Antibody-Drug Conjugate) synthesis, facilitates the attachment of cytotoxic drugs to antibodies for precise delivery to targeted cells or proteins. Its cleavable properties ensure controlled drug release, thereby optimizing the efficacy of the ADC.

Fmoc-Val-Ala-PAB-OH (Fmoc-Val-Ala-PAB) is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RGD peptidomimetic-paclitaxel conjugates bearing lysosomally cleavable linkers.

Mc-Val-Ala-PAB, an effective linker, is utilized in antibody-drug-conjugate (ADC).

N-Me-L-Ala-maytansinol used for making antibody-drug conjugate (ADC),is a hydrophobic, cell permeable payload.

Azide-PEG3-C1-Ala is a PEG-based linker for PROTACs, joining two essential ligands to form PROTAC molecules, and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Azido-PEG3-Ala-Boc, a PEG-based linker for PROTACs, joins two essential ligands necessary for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG5-Ala-Ala-Asn-PAB is a cleavable 5-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB is a cleavable three-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-PEG4-Ala-Ala-Asn-PAB is a cleavable four-unit polyethylene glycol (PEG) linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Aloc-D-Ala-Phe-Lys(Aloc)-PAB-PNP is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs), innovative therapeutic agents that combine the targeting ability of antibodies with potent cytotoxic drugs.

Boc-Val-Ala-PAB-PNP is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. This cleavable compound efficiently facilitates drug-attachment to antibodies, allowing for targeted therapeutic delivery and release, thus playing a crucial role in ADC development.

Fmoc-Ala-Ala-Asn-PABC-PNP is a cleavable peptide ADC linker [1].

MC-Val-Ala-PAB-PNP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

D-Ala-Lys-AMCA hydrochloride, a known substrate of proton-coupled oligopeptide transporter 1 (PEPT1), emits blue fluorescence and may be transported into Caco-2 cells and liver cancer cells.

Azido-PEG4-Ala-Ala-Asn(Trt)-PAB is a PEG derivative conjugated with a peptide via an amide bond. The azide group on the PEG end enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

Enkephalin-met, ala(2)- is a synthetic analog of methionine enkephalin.

Fmoc-PEG3-Ala-Ala-Asn(Trt)-PAB-PNP is a peptide reagent for ADC conjugation featuring a cleavable peptide sequence and a hydrophilic PEG spacer to enhance solubility in aqueous media.

(Ala13)-Apelin-13, catalog number T35374, CAS number 568565-11-7, is a valuable organic compound for life sciences research.

Fmoc-Ala-Glu-Asn-Lys-NH2 is a peptide inhibitor that selectively targets asparagine endopeptidase (AEP) and inhibits the cleavage of amyloid precursor protein (APP). AEP, a pH-controlled cysteine proteinase, plays a crucial role in the proteolytic processing of APP, and its activity is enhanced during the aging process [1].

Fmoc-Val-Ala-PAB-PNP is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs).

Z-Ala-Ala-Asn-AMC, also known as Cbz-Ala-Ala-Asn-AMC, serves as a substrate for legumain. The overexpression of legumain in 293 HEK-Leg cells results in efficient cleavage of Cbz-Ala-Ala-Asn-AMC.

H-β-Ala-AMC TFA is a substrate for aminopeptidase and serves as a building block for synthesizing the fluorogenic vanin I substrate [pantothenate-AMC].

Ala-Ala-Pro-Val-chloromethylketone serves as an irreversible inhibitor of human neutrophil elastase (NE), utilized in researching chronic inflammatory airway diseases.