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Anti-Phospho-MEF2D (Ser180) Polyclonal Antibody
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Catalog No. TMAB-10976
Anti-Phospho-MEF2D (Ser180) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MEF2D (Ser180). Anti-Phospho-MEF2D (Ser180) Polyclonal Antibody can be used in WB.
Anti-Phospho-MEF2D (Ser180) Polyclonal Antibody
Anti-Phospho-MEF2D (Ser180) Polyclonal Antibody
😃Good
Catalog No. TMAB-10976
Anti-Phospho-MEF2D (Ser180) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MEF2D (Ser180). Anti-Phospho-MEF2D (Ser180) Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-MEF2D (Ser180) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MEF2D (Ser180). Anti-Phospho-MEF2D (Ser180) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Note=Translocated by HDAC4 to nuclear dots. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | MEF2D is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human MEF2D around the phosphorylation site of Ser180 |
| Antigen Species | Human |
| Gene Name | MEF2D |
| Gene ID | |
| Protein Name | Myocyte-specific enhancer factor 2D |
| Uniprot ID | |
| Function | Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis (By similarity). |
| Molecular Weight | Theoretical: 57 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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