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Anti-IGF2R/M6PR Polyclonal Antibody 2
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Catalog No. TMAB-07546
Anti-IGF2R/M6PR Polyclonal Antibody 2 is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM.
Anti-IGF2R/M6PR Polyclonal Antibody 2
Anti-IGF2R/M6PR Polyclonal Antibody 2
😃Good
Catalog No. TMAB-07546
Anti-IGF2R/M6PR Polyclonal Antibody 2 is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-IGF2R/M6PR Polyclonal Antibody 2 is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 5μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Lysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
| Immunogen | KLH conjugated synthetic peptide: human IGF2R |
| Antigen Species | Human |
| Gene Name | IGF2R |
| Gene ID | |
| Protein Name | Cation-independent mannose-6-phosphate receptor |
| Uniprot ID | |
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4. |
| Molecular Weight | Theoretical: 300 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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