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Anti-IGF2R/M6PR Polyclonal Antibody 2

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Catalog No. TMAB-07546 Copy Product Info
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Anti-IGF2R/M6PR Polyclonal Antibody 2 is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM.
Anti-IGF2R/M6PR Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IGF2R/M6PR Polyclonal Antibody 2 is a Rabbit antibody targeting IGF2R/M6PR. Anti-IGF2R/M6PR Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 5μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationLysosome membrane. Colocalized with DPP4 in internalized cytoplasmic vesicles adjacent to the cell surface.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundTransport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IGF2R
Antigen Species
Human
Gene Name
IGF2R
Gene ID
Protein Name
Cation-independent mannose-6-phosphate receptor
Uniprot ID
Function
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. This receptor also binds IGF2. Acts as a positive regulator of T-cell coactivation, by binding DPP4.
Chemical Properties
Molecular WeightTheoretical: 300 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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