Anti-Nectin 3 Polyclonal Antibody is a Rabbit antibody targeting Nectin 3. Anti-Nectin 3 Polyclonal Antibody can be used in WB.

IgG

Human,Mouse (predicted:Rat,Cow,Rabbit)

1. Sample: Huvec (Human) Cell Lysate at 30 μg
Primary: Anti-Nectin 3 (TMAB-09331) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD
2. Sample: Epididymis (Mouse) Lysate at 40 μg
Primary: Anti-Nectin 3 (TMAB-09331) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 55 kD
Observed band size: 55 kD

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human Nectin 3

Human

NECTIN3

Nectin-3

Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body.