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Anti-Phospho-Histone H1oo (Ser20) Polyclonal Antibody

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Catalog No. TMAB-10792

Anti-Phospho-Histone H1oo (Ser20) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Histone H1oo (Ser20). Anti-Phospho-Histone H1oo (Ser20) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Phospho-Histone H1oo (Ser20) Polyclonal Antibody

Anti-Phospho-Histone H1oo (Ser20) Polyclonal Antibody

😃Good
Catalog No. TMAB-10792
Anti-Phospho-Histone H1oo (Ser20) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Histone H1oo (Ser20). Anti-Phospho-Histone H1oo (Ser20) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-Histone H1oo (Ser20) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Histone H1oo (Ser20). Anti-Phospho-Histone H1oo (Ser20) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Chromosome.
Tissue SpecificityOocyte-specific.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthesised phosphopeptide: human H1FOO around the phosphorylation site of Ser20
Antigen Species
Human
Gene Name
H1-8
Gene ID
Protein Name
Histone H1.8
Uniprot ID
Function
May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.
Chemical Properties
Molecular WeightTheoretical: 36 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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