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Anti-IL7 Monoclonal Antibody-Biotin
(Synonyms: Interleukin-7) Copy Product Info
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Synonyms: Interleukin-7
Catalog No. TMAZ-0206B Copy Product Info
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Anti-IL7 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting IL7. Anti-IL7 Monoclonal Antibody-Biotin can be used in FCM.
Anti-IL7 Monoclonal Antibody-Biotin
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μg | $120 | 12 days | 12 days | |
| 50 μg | $143 | 12 days | 12 days | |
| 100 μg | $201 | 12 days | 12 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-IL7 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting IL7. Anti-IL7 Monoclonal Antibody-Biotin can be used in FCM. |
| Synonyms | Interleukin-7 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10^6 cells for FCM |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL7 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis (PubMed: 25870237, PubMed: 7527823). Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG (PubMed: 8128231). Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5 (PubMed: 18523275, PubMed: 20974963) |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | IL7 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Drug Target |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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