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Anti-5HT3A Receptor Polyclonal Antibody 2

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Catalog No. TMAB-02107
Alias Serotonin-gated ion channel receptor 3a, Serotonin receptor 3A, Serotonin receptor 3, Serotonin gated ion channel receptor, HTR-3A, Htr3a, HTR3, HTR 3, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3, 5-HT3R, 5HT3R, 5HT3A_HUMAN, 5-HT3-A, 5-HT3A, 5HT3 serotonin receptor, 5-HT-3, 5HT receptor, 5HT 3A, 5HT 3, 5 hydroxytryptamine(serotonin) receptor 3A, 5 Hydroxytryptamine receptor 3, 5 HT3RA, 5 HT3R, 5 HT3A receptor, 5 HT3A, 5 HT3, 5 HT 3

Anti-5HT3A Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting 5HT3A Receptor. Anti-5HT3A Receptor Polyclonal Antibody 2 can be used in WB.

Anti-5HT3A Receptor Polyclonal Antibody 2

Anti-5HT3A Receptor Polyclonal Antibody 2

Copy Product Info
😃Good
Catalog No. TMAB-02107Alias Serotonin-gated ion channel receptor 3a, Serotonin receptor 3A, Serotonin receptor 3, Serotonin gated ion channel receptor, HTR-3A, Htr3a, HTR3, HTR 3, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3, 5-HT3R, 5HT3R, 5HT3A_HUMAN, 5-HT3-A, 5-HT3A, 5HT3 serotonin receptor, 5-HT-3, 5HT receptor, 5HT 3A, 5HT 3, 5 hydroxytryptamine(serotonin) receptor 3A, 5 Hydroxytryptamine receptor 3, 5 HT3RA, 5 HT3R, 5 HT3A receptor, 5 HT3A, 5 HT3, 5 HT 3
Anti-5HT3A Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting 5HT3A Receptor. Anti-5HT3A Receptor Polyclonal Antibody 2 can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-5HT3A Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting 5HT3A Receptor. Anti-5HT3A Receptor Polyclonal Antibody 2 can be used in WB.
SynonymsSerotonin-gated ion channel receptor 3a, Serotonin receptor 3A, Serotonin receptor 3, Serotonin gated ion channel receptor, HTR-3A, Htr3a, HTR3, HTR 3, 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3, 5-HT3R, 5HT3R, 5HT3A_HUMAN, 5-HT3-A, 5-HT3A, 5HT3 serotonin receptor, 5-HT-3, 5HT receptor, 5HT 3A, 5HT 3, 5 hydroxytryptamine(serotonin) receptor 3A, 5 Hydroxytryptamine receptor 3, 5 HT3RA, 5 HT3R, 5 HT3A receptor, 5 HT3A, 5 HT3, 5 HT 3
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
Sample:
Lane 1: Stomach (Mouse) Tissue Lysate at 40 μg
Lane 2: Spinal cord (Rat) TissueLysate at 40 μg
Lane 3: Stomach (Rat) Tissue Lysate at 40 μg
Lane 4: Small intestine (Rat) Tissue Lysate at 40 μg
Lane 5: BV2 (Mouse) Cell Lysate at 30 μg
Lane 6: U251 (Human) Cell Lysate at 30 μg
Lane 7: SH-SY5Y (Human) Cell Lysate at 30 μg
Primary: Anti-5-HTR3 (TMAB-02107) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 53 kD
Observed band size: 50 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Tissue SpecificityExpressed in brain. Higher levels of expression are observed in the cerebellum, occipital cortex and frontal cortex.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. Belongs to the ligand-gated ionic channel (TC 1.A.9) family.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human 5-HTR3
Antigen Species
Human
Gene Name
HTR3A
Gene ID
Protein Name
5-hydroxytryptamine receptor 3A
Uniprot ID
Function
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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