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Anti-PRCC/Papillary renal cell carcinoma Polyclonal Antibody

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Catalog No. TMAB-11711

Anti-PRCC/Papillary renal cell carcinoma Polyclonal Antibody is a Rabbit antibody targeting PRCC/Papillary renal cell carcinoma. Anti-PRCC/Papillary renal cell carcinoma Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-PRCC/Papillary renal cell carcinoma Polyclonal Antibody

Anti-PRCC/Papillary renal cell carcinoma Polyclonal Antibody

Copy Product Info
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Catalog No. TMAB-11711
Anti-PRCC/Papillary renal cell carcinoma Polyclonal Antibody is a Rabbit antibody targeting PRCC/Papillary renal cell carcinoma. Anti-PRCC/Papillary renal cell carcinoma Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-PRCC/Papillary renal cell carcinoma Polyclonal Antibody is a Rabbit antibody targeting PRCC/Papillary renal cell carcinoma. Anti-PRCC/Papillary renal cell carcinoma Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
1. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (PRCC/Papillary renal cell carcinoma) Polyclonal Antibody, Unconjugated (TMAB-11711) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
2. Sample: 293T (Human) Cell Lysate at 30 μg
Primary: Anti-PRCC (TMAB-11711) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 52 kD
Observed band size: 52 kD
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityUbiquitous in fetal and adult tissues.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PRCC
Antigen Species
Human
Gene Name
PRCC
Gene ID
Protein Name
Proline-rich protein PRCC
Uniprot ID
Function
May regulate cell cycle progression through interaction with MAD2L2.
Chemical Properties
Molecular WeightTheoretical: 52 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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