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Anti-Phospho-CPI17 alpha (Thr38) Polyclonal Antibody
Catalog No. TMAB-10535 Copy Product Info
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Anti-Phospho-CPI17 alpha (Thr38) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CPI17 alpha (Thr38). Anti-Phospho-CPI17 alpha (Thr38) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-CPI17 alpha (Thr38) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-10535
Anti-Phospho-CPI17 alpha (Thr38) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CPI17 alpha (Thr38). Anti-Phospho-CPI17 alpha (Thr38) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-Phospho-CPI17 alpha
(Thr38) Polyclonal Antibody
(Thr38) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Phospho-CPI17 alpha (Thr38) Polyclonal Antibody is a Rabbit antibody targeting Phospho-CPI17 alpha (Thr38). Anti-Phospho-CPI17 alpha (Thr38) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (phospho-CPI17 alpha (Thr38)) Polyclonal Antibody, Unconjugated (TMAB-10535) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm |
| Tissue Specificity | Isoform 1 is detected in aorta and testis.Isoform 2 is detected in aorta. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011] |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human CPI17 alpha around the phosphorylation site of Thr38 |
| Antigen Species | Human |
| Gene Name | PPP1R14A |
| Gene ID | |
| Protein Name | Protein phosphatase 1 regulatory subunit 14A |
| Uniprot ID | |
| Function | nhibitor of PPP1CA. Has over 1000-fold higherinhibitory activity when phosphorylated, creating a molecularswitch for regulating the phosphorylation status of PPP1CAsubstrates and smooth muscle contraction. |
| Molecular Weight | Theoretical: 17 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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