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Anti-HAND2 Polyclonal Antibody

Catalog No. TMAB-06880 Copy Product Info
🥰Excellent
Anti-HAND2 Polyclonal Antibody is a Rabbit antibody targeting HAND2. Anti-HAND2 Polyclonal Antibody can be used in WB.

Anti-HAND2 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-06880

Anti-HAND2 Polyclonal Antibody is a Rabbit antibody targeting HAND2. Anti-HAND2 Polyclonal Antibody can be used in WB.

Anti-HAND2 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HAND2 Polyclonal Antibody is a Rabbit antibody targeting HAND2. Anti-HAND2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit,Sheep)
Verified Activity
Sample:
Lane 1: Heart (Mouse) Lysate at 40 μg
Primary: Anti-HAND2 (TMAB-06880) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 26 kD
Observed band size: 26 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityHeart.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundEssential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human HAND2
Antigen Species
Human
Gene Name
HAND2
Gene ID
Protein Name
Heart-and neural crest derivatives-expressed protein 2
Uniprot ID
Function
Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3' (By similarity).
Chemical Properties
Molecular WeightTheoretical: 24 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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