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Anti-MAP1A Polyclonal Antibody

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Catalog No. TMAB-08555

Anti-MAP1A Polyclonal Antibody is a Rabbit antibody targeting MAP1A. Anti-MAP1A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.

Anti-MAP1A Polyclonal Antibody

Anti-MAP1A Polyclonal Antibody

😃Good
Catalog No. TMAB-08555
Anti-MAP1A Polyclonal Antibody is a Rabbit antibody targeting MAP1A. Anti-MAP1A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MAP1A Polyclonal Antibody is a Rabbit antibody targeting MAP1A. Anti-MAP1A Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse)
Application
IHC-P
IHC-Fr
IF
FCM
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor.
Tissue SpecificityMost abundant in placenta, lung and ovary.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundA major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. There are three isoforms of human LC3 (named MAP1LC3A, MAP1LC3B, and MAP1LC3C), which exhibit different tissue distributions. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MAP1A heavy chain
Antigen Species
Human
Gene Name
MAP1LC3C
Gene ID
440738
Protein Name
Microtubule-associated proteins 1A/1B light chain 3C
Uniprot ID
Q9BXW4
Function
Probably involved in formation of autophagosomal vacuoles (autophagosomes).
Chemical Properties
Molecular WeightTheoretical: 326 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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