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Anti-Sin3b Polyclonal Antibody

Catalog No. TMAB-12802 Copy Product Info
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Anti-Sin3b Polyclonal Antibody is a Rabbit antibody targeting Sin3b. Anti-Sin3b Polyclonal Antibody can be used in WB.

Anti-Sin3b Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-12802

Anti-Sin3b Polyclonal Antibody is a Rabbit antibody targeting Sin3b. Anti-Sin3b Polyclonal Antibody can be used in WB.

Anti-Sin3b Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Sin3b Polyclonal Antibody is a Rabbit antibody targeting Sin3b. Anti-Sin3b Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Cow,Horse,Sheep)
Verified Activity
Sample: 293T (Human) Cell Lysate at 30 μg
Primary: Anti-Sin3b (TMAB-12802) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 133 kD
Observed band size: 133 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus (By similarity).
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundActs as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Sin3b
Antigen Species
Human
Gene Name
SIN3B
Gene ID
Protein Name
Paired amphipathic helix protein Sin3b
Uniprot ID
Function
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity).
Chemical Properties
Molecular WeightTheoretical: 133 kDa. Actual: 133 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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