Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-GCAP1 Polyclonal Antibody
Catalog No. TMAB-06372 Copy Product Info
🥰Excellent
Anti-GCAP1 Polyclonal Antibody is a Rabbit antibody targeting GCAP1. Anti-GCAP1 Polyclonal Antibody can be used in WB.
Anti-GCAP1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-06372
Anti-GCAP1 Polyclonal Antibody is a Rabbit antibody targeting GCAP1. Anti-GCAP1 Polyclonal Antibody can be used in WB.
Anti-GCAP1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GCAP1 Polyclonal Antibody is a Rabbit antibody targeting GCAP1. Anti-GCAP1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Cow,Horse,Sheep) |
| Verified Activity | 1. Sample: Eye (Mouse) Lysate at 40 μg Primary: Anti-GCAP1 (TMAB-06372) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 23 kD Observed band size: 25 kD 2. Sample: Cerebrum (Rat) Lysate at 40 μg Primary: Anti-GCAP1 (TMAB-06372) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 23 kD Observed band size: 23 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane. |
| Tissue Specificity | Retina; cone outer and inner segments, in particular, in disk membrane regions, and to a lesser extent rod inner and outer segments. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | intracellular stimulation of guanylate cyclase (GC) by calcium, a key event in the recovery of the dark state of rod photoreceptors after exposure to light, is mediated by guanylate cyclase-activating protein (GCAP1). GCAPs are calcium-The binding proteins belonging to the calmodulin superfamily. GCAP1 is a calcium-binding protein that stimulates synthesis of c-GMP in photoreceptors. GCAP1 is present in rod and cone photoreceptor outer segments where phototransduction occurs. In contrast to other calcium-binding proteins from the calmodulin superfamily, the calcium-free form of GCAP1 stimulates the effector enzyme. By molecular cloning of human and mouse GCAP cDNA, the known mammalian GCAPs are found to be more than 90% similar, consisting of 201 to 205 amino acids, and containing three identically conserved calcium-binding sites. A related protein, GCAP2, is detectable only in the retina and results from a gene duplication event. |
| Immunogen | KLH conjugated synthetic peptide: human GCAP1 |
| Antigen Species | Human |
| Gene Name | GUCA1A |
| Gene ID | |
| Protein Name | Guanylyl cyclase-activating protein 1 |
| Uniprot ID | |
| Function | Stimulates guanylyl cyclase 1 (GC1) when free calcium ions concentration is low and inhibits GC1 when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of GC is a key event in recovery of the dark state of rod photoreceptors following light exposure. |
| Molecular Weight | Theoretical: 23 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-GCAP1 Polyclonal Antibody | purchase Anti-GCAP1 Polyclonal Antibody | Anti-GCAP1 Polyclonal Antibody cost | order Anti-GCAP1 Polyclonal Antibody | Anti-GCAP1 Polyclonal Antibody molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.