Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-IL10 Monoclonal Antibody-Biotin (Synonyms: Interleukin-10, Cytokine synthesis inhibitory factor)
Catalog No. TMAZ-0029B Copy Product Info
🥰Excellent
Anti-IL10 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting IL10. Anti-IL10 Monoclonal Antibody-Biotin can be used in ELISA,FCM,IF.
Anti-IL10 Monoclonal Antibody-Biotin
Copy Product Info🥰Excellent
Catalog No. TMAZ-0029B
Synonyms Interleukin-10, Cytokine synthesis inhibitory factor
Anti-IL10 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting IL10. Anti-IL10 Monoclonal Antibody-Biotin can be used in ELISA,FCM,IF.
Anti-IL10 Monoclonal Antibody-Biotin
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μg | $196 | 12 days | 12 days | |
| 50 μg | $236 | 12 days | 12 days | |
| 100 μg | $330 | 12 days | 12 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IL10 Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting IL10. Anti-IL10 Monoclonal Antibody-Biotin can be used in ELISA,FCM,IF. |
| Synonyms | Interleukin-10, Cytokine synthesis inhibitory factor |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of IL10 overexpressed 353F cells with TMAZ-0029B, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10E6 cells for FCM; 1 ng/μl for ELISA |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of IL10 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3 (PubMed: 16982608). In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators (PubMed: 18025162). Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha (PubMed: 11564774, PubMed: 1940799, PubMed: 7512027). Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (PubMed: 8144879). In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity) |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | IL10 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Immunology Research |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-IL10 Monoclonal Antibody-Biotin | purchase Anti-IL10 Monoclonal Antibody-Biotin | Anti-IL10 Monoclonal Antibody-Biotin cost | order Anti-IL10 Monoclonal Antibody-Biotin | Anti-IL10 Monoclonal Antibody-Biotin molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.