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Anti-NPW/Neuropeptide W Polyclonal Antibody

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Catalog No. TMAB-09599

Anti-NPW/Neuropeptide W Polyclonal Antibody is a Rabbit antibody targeting NPW/Neuropeptide W. Anti-NPW/Neuropeptide W Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-NPW/Neuropeptide W Polyclonal Antibody

Anti-NPW/Neuropeptide W Polyclonal Antibody

😃Good
Catalog No. TMAB-09599
Anti-NPW/Neuropeptide W Polyclonal Antibody is a Rabbit antibody targeting NPW/Neuropeptide W. Anti-NPW/Neuropeptide W Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-NPW/Neuropeptide W Polyclonal Antibody is a Rabbit antibody targeting NPW/Neuropeptide W. Anti-NPW/Neuropeptide W Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Cow)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted
Tissue SpecificityDetected at high levels in the substantia nigra, fetal kidney and trachea; at lower levels in testis, uterus, ovary and placenta. Not detectable in many regions of the central nervous system. Also detected at high levels in lymphoblastic leukemia and colorectal adenocarcinoma.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundNPW is a 165 amino acid secreted protein that is cleaved into two chains: neuropeptide W-23 (also designated NPW23 or L8) and neuropeptide W-30 (also known as NPW30 or L8C). Both NPW neuropeptides activate G-protein coupled receptors in the central nervous system to enhance cortisol secretion. Highly expressed in lymphoblastic leukemia, colorectal adenocarcinoma, fetal kidney, trachea and substantia nigra, NPW is also found at low levels in placenta, ovary, testis and uterus. NPW functions in organization of neuroendocrine signals and is also thought to enhance food and water intake as well as stress responses. The gene encoding NPW maps to human chromosome 16p13.3.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Neuropeptide W
Antigen Species
Human
Gene Name
NPW
Gene ID
Protein Name
Neuropeptide W
Uniprot ID
Function
NPW is processed into 23- and 30-amino acid neuropeptides that bind and activate two G-protein coupled receptors in the central nervous system. The neuropeptides have been shown to enhance cortisol secretion from adrenal cells through the adenylate cyclase/protein kinase A signaling cascade. The preproprotein is translated using a non-AUG initiation codon that is inferred from analyses of the mouse ortholog.
Chemical Properties
Molecular WeightTheoretical: 3 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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