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Anti-Phospho-SCNN1B (Thr615) Polyclonal Antibody
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Catalog No. TMAB-11269 Copy Product Info
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Anti-Phospho-SCNN1B (Thr615) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SCNN1B (Thr615). Anti-Phospho-SCNN1B (Thr615) Polyclonal Antibody can be used in WB,ICC/IF,FCM.
Anti-Phospho-SCNN1B
(Thr615) Polyclonal Antibody
(Thr615) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-Phospho-SCNN1B (Thr615) Polyclonal Antibody is a Rabbit antibody targeting Phospho-SCNN1B (Thr615). Anti-Phospho-SCNN1B (Thr615) Polyclonal Antibody can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit,GuineaPig) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:100-500; FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | SCNN1B is a subunit of the epithelial sodium channel, ENaC. ENac has high sodium selectivity, low conductance, and amiloride sensitivity. The functional channel of ENaC is composed of at least 3 subunits, alpha (SCNN1A), beta (SCNN1B), and gamma (SCNN1G). The 3 subunits show sequence similarities to one another, indicating descent from a common ancestral gene. Each encodes a protein containing 2 transmembrane domains, with intracellular amino and carboxyl termini. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human SCNN1B around the phosphorylation site of Thr615 |
| Antigen Species | Human |
| Gene Name | SCNN1B |
| Gene ID | |
| Protein Name | Epithelial sodium channel subunit beta |
| Uniprot ID | |
| Function | Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. |
| Molecular Weight | Theoretical: 73 kDa. Actual: 73 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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