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Anti-MGEA5 Polyclonal Antibody
😃Good
Catalog No. TMAB-08789
Anti-MGEA5 Polyclonal Antibody is a Rabbit antibody targeting MGEA5. Anti-MGEA5 Polyclonal Antibody can be used in WB.
Anti-MGEA5 Polyclonal Antibody
Anti-MGEA5 Polyclonal Antibody
😃Good
Catalog No. TMAB-08789
Anti-MGEA5 Polyclonal Antibody is a Rabbit antibody targeting MGEA5. Anti-MGEA5 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-MGEA5 Polyclonal Antibody is a Rabbit antibody targeting MGEA5. Anti-MGEA5 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 3: Nucleus. Isoform 1: Cytoplasm. |
| Tissue Specificity | Ubiquitous. Shows highest expression in the brain, placenta and pancreas. [PTM] Proteolytically cleaved by caspase-3. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications (Gao et al., 2001 [PubMed 11148210]).[supplied by OMIM, Mar 2008]. |
| Immunogen | KLH conjugated synthetic peptide: human MGEA5 |
| Antigen Species | Human |
| Gene Name | OGA |
| Gene ID | |
| Protein Name | Protein O-GlcNAcase |
| Uniprot ID | |
| Function | Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3 (By similarity). |
| Molecular Weight | Theoretical: 103 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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