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Anti-CDC2L1 Polyclonal Antibody

🥰Excellent
Catalog No. TMAB-04122

Antibody Type: Rabbit Polyclonal
Application: IHC-P,IHC-Fr,IF
Reactivity: Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit)

Anti-CDC2L1 Polyclonal Antibody

Anti-CDC2L1 Polyclonal Antibody

🥰Excellent
Catalog No. TMAB-04122
Antibody Type: Rabbit Polyclonal
Application: IHC-P,IHC-Fr,IF
Reactivity: Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit)
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Product Introduction

Bioactivity
Description
Anti-CDC2L1 Polyclonal Antibody is a Rabbit antibody targeting CDC2L1. Anti-CDC2L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus.
Tissue SpecificityExpressed ubiquitously. Some evidence of isoform-specific tissue distribution.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSummary: This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L2, a nearly identical gene in the same chromosomal region. The gene loci including this gene, CDC2L2, as well as metalloprotease MMP21/22, consist of two identical, tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L2 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Several alternatively spliced variants of this gene have been reported. [provided by RefSeq, Jul 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CDC2L1
Antigen Species
Human
Gene Name
CDK11B
Gene ID
Protein Name
Cyclin-dependent kinase 11B
Function
Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
Chemical Properties
Molecular WeightTheoretical: 93 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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