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Anti-Integrin beta 5 Polyclonal Antibody
Catalog No. TMAB-07753 Copy Product Info
🥰Excellent
Anti-Integrin beta 5 Polyclonal Antibody is a Rabbit antibody targeting Integrin beta 5. Anti-Integrin beta 5 Polyclonal Antibody can be used in WB.
Anti-Integrin beta 5 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-07753
Anti-Integrin beta 5 Polyclonal Antibody is a Rabbit antibody targeting Integrin beta 5. Anti-Integrin beta 5 Polyclonal Antibody can be used in WB.
Anti-Integrin beta 5 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
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| Description | Anti-Integrin beta 5 Polyclonal Antibody is a Rabbit antibody targeting Integrin beta 5. Anti-Integrin beta 5 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | 1. Sample: Lung (Mouse) Lysate at 40 μg Primary: Anti-Integrin beta 5 (TMAB-07753) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 86 kD Observed band size: 126 kD 2. Sample: A549 (Human) Cell Lysate at 30 μg Raw264.7 (Mouse) Cell Lysate at 30 μg NIH/3T3 (Mouse) Cell Lysate at 30 μg Primary: Anti-Integrin beta 5 (TMAB-07753) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 86 kD Observed band size: 126 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces. They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit. Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature. Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell surface receptors, they bind ligands with very low affinity. Due to their weak individual binding, integrins need to cluster and bind in groups in order to effectively bind the ECM. Integrins bind many different ligands including laminin. Each integrin is made up of a large N terminal extracellular domain that binds the ECM ligand and a small C terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function. The integrin subunit beta 5 has only been associated with the alpha v subunit to form the alpha v beta 5 heterodimer. This integrin mediates cell adhesion to vitronectin and also recognizes fibronectin when the integrin is activated. This integrin is found in a variety of cells in most normal tissue. |
| Immunogen | KLH conjugated synthetic peptide: human Integrin beta 5 |
| Antigen Species | Human |
| Gene Name | ITGB5 |
| Gene ID | |
| Protein Name | Integrin beta-5 |
| Uniprot ID | |
| Function | Integrin alpha-V/beta-5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. |
| Molecular Weight | Theoretical: 86 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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