Shopping Cart
Remove All
Your shopping cart is currently empty
Anti-TopBP1 Polyclonal Antibody
Catalog No. TMAB-13675 Copy Product Info
🥰Excellent
Anti-TopBP1 Polyclonal Antibody is a Rabbit antibody targeting TopBP1. Anti-TopBP1 Polyclonal Antibody can be used in WB.
Anti-TopBP1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-13675
Anti-TopBP1 Polyclonal Antibody is a Rabbit antibody targeting TopBP1. Anti-TopBP1 Polyclonal Antibody can be used in WB.
Anti-TopBP1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
Add to Cart
Add to Quotation
For research use only—not for human use. No sales to individuals. Use as intended only.
Resource Download
Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-TopBP1 Polyclonal Antibody is a Rabbit antibody targeting TopBP1. Anti-TopBP1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Cow,Rabbit,Sheep) |
| Verified Activity | Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-TopBP1 (TMAB-13675) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 171 kD Observed band size: 171 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm; cytoskeleton; centrosome. Cytoplasm; cytoskeleton; spindle pole. Chromosome. Detected on unpaired autosomes in meiotic prophase cells. Detected on X and Y chromosomes during later stages of prophase. Colocalizes with ATR and H2AFX at unsynapsed chromosome cores during prophase (By similarity). Has a uniform nuclear distribution during G phase. Colocalizes with BRCA1 at stalled replication forks during S phase. In mitotic cells it colocalizes with BRCA1 at spindle poles and centrosomes during metaphase and anaphase. Detected in discrete foci together with PML and numerous DNA repair enzymes after DNA damage by alkylating agents, UV or gamma irradiation. |
| Tissue Specificity | Highly expressed in heart, brain, placenta, lung and kidney. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Required for DNA replication. Plays a role in the rescue of stalled replication forks and checkpoint control. Binds double-stranded DNA breaks and nicks as well as single-stranded DNA. Recruits the SWI/SNF chromatin remodeling complex to E2F1-responsive promoters. Down-regulates E2F1 activity and inhibits E2F1-dependent apoptosis during G1/S transition and after DNA damage. Induces a large increase in the kinase activity of ATR. |
| Immunogen | KLH conjugated synthetic peptide: human TopBP1 |
| Antigen Species | Human |
| Gene Name | TOPBP1 |
| Gene ID | |
| Protein Name | DNA topoisomerase 2-binding protein 1 |
| Uniprot ID |
| Molecular Weight | Theoretical: 171 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Calculator
Preview
Related Tags: buy Anti-TopBP1 Polyclonal Antibody | purchase Anti-TopBP1 Polyclonal Antibody | Anti-TopBP1 Polyclonal Antibody cost | order Anti-TopBP1 Polyclonal Antibody | Anti-TopBP1 Polyclonal Antibody molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.