Anti-CSNK1G2 Polyclonal Antibody is a Rabbit antibody targeting CSNK1G2. Anti-CSNK1G2 Polyclonal Antibody can be used in WB.

IgG

Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Rabbit)

1. Sample:
Uterus (Mouse) Lysate at 40 μg
Primary: Anti-CSNK1G2 (TMAB-04729) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kD
Observed band size: 49 kD
2. Sample:
Lane 1: Rat Muscle tissue lysates
Lane 2: Rat Cerebrum tissue lysates
Primary: Anti-CSNK1G2 (TMAB-04729) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 47 kDa
Observed band size: 50 kDa

WB: 1:500-2000

Polyclonal

KLH conjugated synthetic peptide: human CSNK1G2

Human

CSNK1G2

Casein kinase I isoform gamma-2

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis.